2020: Physiologically Based, Pharmacokinetic (PBPK) Modeling Approaches to Drug Delivery [MATH891.007]


Course title Pharmacokinetics and Physiologically Based Pharmacokinetics Modeling and Simulation: Principle and Applications
Course Offering: MATH 891.007, GNET/BCB 891.007
Instructors: Yanguang (Carter) Cao, Greg Forest, and Anne Talkington
Course description: The primary objectives of this course include:
• Gain an understanding of the basic concept and principles of pharmacokinetics
• Learn about the basics of pharmacokinetics and pharmacodynamics analysis
• Learn about the foundations of physiologically based pharmacokinetic models
• Understand the process and rules of building a physiologically based pharmacokinetic model for a variety of therapeutic modalities (small molecules, protein drugs, and nanoparticles)
• Hands-on analysis of pharmacokinetics and physiologically based pharmacokinetics
• 2-3 assignments for analyzing real world patient pharmacokinetic data
• Grading: In-class participation and homework assignments
 Prerequisites  Current enrollment in graduate program of any participating Department in the NIH T32 BD2K graduate training program
Course Dates Tuesdays, Jan 21 – April 3
Meeting pattern 3:00-5:10pm
Location: TBD
Syllabus: BD2K Module PK AND PBPK – Carter Cao